Endocrine diseases include Diabetes mellitus (insulin dependent), Diabetes insipidus (non-insulin dependent), Addison disease, Cushing disease, Hyperthyroidism, and Hypothyroidism. The dental management of patients with endocrine disease involves assessment and treatment of oral mucosal disease and infection associated with altered endocrine function, a consideration of the necessary precautions needed during the provision of dental treatment, and the appropriate management of medical emergencies that can arise during treatment.